1.
Int J Parasitol
; 26(12): 1393-5, 1996 Dec.
Artigo
em Inglês
| MEDLINE
| ID: mdl-9024890
RESUMO
Persistence of down regulation of granuloma size was studied in mice chronically infected with Schistosoma mansoni and cured by chemotherapy. The animals were reinfected at 20-, 50-, 110-, and 140-day intervals after treatment, and sacrificed 60 days post-infection. Reinfected animals were able to modulate the granulomatous inflammatory response, thus preventing a new acute phase. These findings may contribute to the explanation for the decrease of morbidity from human schistosomiasis seen in endemic areas following mass treatment.
Assuntos
Granuloma/parasitologia , Hepatopatias Parasitárias/patologia , Oxamniquine/uso terapêutico , Esquistossomose mansoni/tratamento farmacológico , Esquistossomose mansoni/patologia , Animais , Granuloma/etiologia , Inflamação , Hepatopatias Parasitárias/tratamento farmacológico , Camundongos , Esquistossomose mansoni/complicações , Esquistossomicidas/uso terapêutico
2.
Rev Inst Med Trop Sao Paulo
; 38(4): 303-5, 1996.
Artigo
em Inglês
| MEDLINE
| ID: mdl-9216114